"Ten simple rules of getting published"

"Rule 6: The ingredients of good science are obvious—novelty of research topic, comprehensive coverage of the relevant literature, good data, good analysis including strong statistical support, and a thought-provoking discussion. The ingredients of good science reporting are obvious—good organization, the appropriate use of tables and figures, the right length, writing to the intended audience—do not ignore the obvious."

Read more on PLoS Computational Biology

Hey, don't restart my computer for me!

This morning, when I arrived at my office, I expected to see my simulation completed. Instead, I found that my PC was restarted and part of the simulation was terminated and unfinished. As I logged in, a message arised from the lower right corner:"you computer was recently updated, which required an automatic restart". Hey! I know it will make my computer better but my simulation is also very crucial to me.

[Ref List] Combining linkage and association

Fulker DW, Cherny SS, Sham PC, Hewitt JK (1999) Combined Linkage and Association Sib-Pair Analysis for Quantitative Traits. Am. J. Hum. Genet. 64:259-267

Zhu G, Duffy DL, Eldridge A, Grace M, Mayne C, O'Gorman L, Aitken JF, Neale MC, Hayward NF, Green AC, Martin NG (1999) A Major Quantitative-Trait Locus for Mole Density Is Linked to the Familial Melanoma Gene CDKN2A: A Maximum-Likelihood Combined Linkage and Association Analysis in Twins and Their Sibs. Am. J. Hum. Genet. 65:483-492

Combined Linkage and Association Tests in Mx
D Posthuma, EJC de Geus, DI Boomsma, MC Neale - Behavior Genetics, 2004

Combined linkage and association analysis in pedigrees
KD Siegmund, H Vora, WJ Gauderman - Genet Epidemiol Suppl, 2001

Combined high resolution linkage and association mapping of quantitative trait loci
R Fan, M Xiong - European Journal of Human Genetics, 2003

Combined association and linkage analysis applied to the APOE locus
M Beekman, D Posthuma, BT Heijmans, N Lakenberg, … - Genetic Epidemiology, 2004

Combined Linkage and Association Mapping of Quantitative Trait Loci by Multiple Markers.
R Fan - Genetics, 2005

How magical!

I just started to appreciate how magical our everyday technology is. Just in a matter of no more than two hundred years, we push a button, tons of things can be done. Just in a matter of no more than 70 years, computers can do so so so many things for us. I don't think I have given credits to all the people that have made these magics happen. Sure, I have heard of some big names. But, what about the great minds behind the IBM thinkpad I am using? What about the great minds behind this convenient Blogger I am using? I was listening to ABBA's "thanks for the music" on my IPOD (another bunch of great geeky minds), and really wanted to change the lyrics to "thanks for the 'techos' ".

I used to think Harry Potter's world is cool. But I think our world is cool enough.

BTW: ABBA, what a great band!

The culture of blogging

From one of my favorite online references wikipedia, the history of blog is smmarized as

Blogging begins
Blogging combined the personal web page with tools to make linking to other pages easier, specifically blogrolls and TrackBacks, as well as comments and afterthoughts. This way, instead of a few people being in control of threads on a forum, or anyone able to start threads on a list, there was a moderating effect that was the personality of the weblog's owner. Justin Hall, who began eleven years of personal blogging in 1994 while a student at Swarthmore College, is generally recognized as one of the earliest bloggers.

The term "weblog" may have been coined by Jorn Barger in December 1997. The horter version, "blog", was coined by Peter Merholz, who, in April or May of 1999, broke the word weblog into the phrase "we blog" in the sidebar of his weblog. [1] This was interpreted as a short form of the noun [2] and also as a verb to blog, meaning "to edit one's weblog or a post to one's weblog". The site Open Diary, while not using the term blog until recently, launched in 1998, had over 2000 diaries by 1999, and near 400 000 as of September 2005. Blog usage spread during 1999, with the word being further popularized by the near-simultaneous arrival of the first hosted weblog tools: Evan Williams and Meg Hourihan's company Pyra Labs launched Blogger (which was purchased by Google in February 2003) and Paul Kedrosky's GrokSoup. As of March 2003, the Oxford English Dictionary included the terms weblog, weblogging and weblogger in their dictionary. [3]

One of the pioneers of the tools that make blogging more than merely websites that scroll is Dave Winer. One of his most important contributions was the creation of servers which weblogs would ping to show that they had been updated. Blog reading utilities use the aggregated update data to show a user when their favorite blogs have new posts.

I started thinking about the use of blogs by people I know.

Content [audience]

• Sharing ideas or opinions [for others]
• logging thoughts [for self]
• Initiate discussions [for self and others]
• logging online resources [for self]
• dumping personal experiences [nobody, maybe]
• ...

Lu, Xun (a Chinese writer) wrote an article titled "a memoir, so to forget" (unofficial title, I made it up. There must be a better translation). The main idea of the title is that the reason he wrote the piece is because he wanted to start the healing from the experiences he accounted in that article. I like this title a lot (sure, the chinese version). The main reason I wrote some of the blog posts is also I want them to be off my mind. (Sooner or later, I probably will write in my blog, "final exam, 3rd drawer") since I am an organizer. Not only I want the physical space surrounding me organized, I also want to have an organized mind. One rule in the principles of getting things organized is that you must have a place to dump. This dumping station should be very accessible (easy to dump), and very visible (hard for you to forget to attend). I also remember a short story I read years ago:

Two cities want to compete for the title of "cleanest city". One prohibits harshly its residents from dumping trash on the street but ends up with trash in every corner. So the mayor goes the other city and sees really clean streets. He wonders how the other mayor has done that. He later found out that, in the other city, the residents were told where to dump.

Naturally, we (should I say "I", just speaking for myself?) need a place to dump. For our mails, for our teaching notes, for our research notes. Now, we (or I) need place to dump our opinions, ideas, feelings, joys, etc. But when I dump, Ialso need to show them. This part of my blogging behavior always makes me think. A friend of mine said that blogging is a subtle way of "showing off" and that is why he does not blog. Well, that is too harsh, or is it? Is the whole culture of blogging driven by people's internal desire to show off? Simply because it is more subtle than most other ways of showing off, it gets such popularity. Or shall I think more positively? People blog because they want to participate in a collective thinking community?